The AIDA's team have been very active this week and proposed many workshops and training session. The main topics concerned essentially Indirect Immunofluorescence and the place that ICT takes in Autoimmune Diseases detection. The AIDA's team consider at the upmost importance to develop an expert system able to analyze Indirect Immunofluorescence images.
The AIDA's project aims to promote the Italo - Tunisian cooperation in research and innovation in the health sector through the application of ICT for diagnosis of autoimmune diseases. The growing complexity in biomedical data management and analysis create the urgency and necessity of using information technologies that support physicians in the diagnostic process. ICTs have been successfully applied in medical imaging. This project aims to use innovative ICT to improve the diagnosis of autoimmune disease.
The AIDA Project makes a validated database of HE-p2 images and data from the IIF test available to the scientific community.
The Pubblic Database "AIDA_HEp-2" is a subset of the full AIDA database, where three physician experts (independently) have expressed unanimous opinion on reporting. This is now available to the scientific community and, to our knowledge until today, it is the HEp-2 images public database larger (1000 patients sera) and rapresentative of the real cases including a variety of single and multiple patterns.
The "AIDA_HEp-2" database was obtained between 01/2013 and 12/2015 in the following Immunology Laboratories:
U.O.C. Patologia Clinica , Ospedale Buccheri La Ferla, Palermo, Italy;
APS-AG, U.O.C. Patologia Clinica , P.O. Sciacca, Italy;
ASP-TP U.O.C. Patologia Clinica, P.O. Trapani, Italy;
U.O.C. Patologia Clinica, Ospedale Civico, Palermo, Italy;
Institut Pasteur, Tunisi, Tunisia;
Ospedale Charles Nicolle, Tunisi, Tunisia;
Ospedale de l’Ariana, Tunisi, Tunisia.
The dataset consists of 1000 patient records and for each of them are reported the following information:
image/s from well were patient sera was prepared;
the negativity or positivity fluorescence intensity of the patient sera;
the staining pattern (single or multiple) for the patient positive sera;
the age and sex of patient (if available);
the image acquisition instrument.
The database contains fluorescence positive sera with a variety of more than twenty staining pattern. In each image can be present single or multiple pattern. The patterns terminology is in accordance with the "International Consensus on ANA Patterns" (ICAP): http://www.anapatterns.org/
The database can be downloaded after registration in download section (http://www.aidaproject.net/downloads) and consists of the following files:
AIDA_HEp-2_Note.pdf;
AIDA_HEp-2_GroundTruth.xls;
AIDA_Article.pdf;
AIDA_Project_Database_HEp-2.zip (from google Drive).
The project A.I.D.A., through its component 5, aims the promotion and enhancement of research, the innovation in the Health Sector and in Tunisia of innovative start ups in the field of ICT applied to Health.
For further information please visit http://elgazala-aida.tn/
Usefull links :
The 3rd international conference on Health Science and Biomedical Systems will take place from November 22-24, 2014 in Florence, Italy. The AIDA project will be present to conference with preliminary results in a paper and talk.
This training course aims to sensitize the public of various scientific backgrounds to the need to improve the methods of autoimmune diseases diagnosis and the importance of multidisciplinary and collaborative approach to reach this goal. Besides base course on immune tolerance mechanisms and breaking of tolerance, different autoimmune diseases and their diagnosis by immunofluorescence will be presented.